Non-infectious inflammatory disorders of the lung (Equine asthma) are among the most common medical conditions affecting horses and are the leading causes of exercise intolerance.
Heaves (severe equine asthma) naturally affects 15% of horses during normal stabling conditions, and it is estimated that up to 75% of horses will present transient or persistent episodes of mild or moderate asthma (Inflammatory Airway Disease, IAD) during their life.
Our research program:
The clinical signs, lung lesions, and the response to therapy observed in heaves shares striking similarities with those observed in asthma. Key discoveries made using this equine disease could elucidate asthma pathophysiology, and possibly leading to the discovery of novel therapeutic targets for human and equine asthma.